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      • This website is for UK Healthcare Professionals only

      This promotional material is intended for UK Healthcare Professionals experienced in the diagnosis and treatment of Chronic Migraine. BOTOX® (botulinum toxin type A) Prescribing Information and adverse event reporting information can be found below.

      +30 YEARS' GLOBAL EXPERIENCE
      ACROSS MULTIPLE INDICATIONS1-4

       

      CHRONIC MIGRAINE

      BOTOX® (botulinum toxin type A) is indicated for the prophylaxis of headaches in adults with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine).5

      +30 YEARS' GLOBAL EXPERIENCE ACROSS MULTIPLE INDICATIONS1-4

      CHRONIC MIGRAINE

      BOTOX® (botulinum toxin type A) is indicated for the prophylaxis of headaches in adults with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine).5

      UK-BCM-240113. DOP: January 2025.

      Chronic migraine: a long and frustrating patient journey6*†

      *This journey is based on clinical observations. Patients may have an entirely different experience in their own journey.
      †Based on a small-scale (N=200) questionnaire-based study of patients presenting with headache.6

      Diagnosing and managing chronic migraine

      Watch a video on the diagnosis of chronic migraine, featuring specialist Dr Andrew Blumenfeld of the Neurology Center, San Diego, US >

      What are the three steps to making a chronic migraine diagnosis? >

      View acute and prophylactic treatment options for migraine, as well as NICE guidance on its management >

      Could your patients with chronic migraine benefit from treatment with BOTOX®?

      A real-life patient treatment journey

      Kayte was diagnosed with chronic migraine at 24, and experienced issues with certain treatments before finding one that suited her.

      Learn about her individual experience in this video, and find out about her experience with BOTOX® >

      Initiating a patient on BOTOX®

      How should you consult your patients who are starting on BOTOX®, and how can you ensure treatment adherence?

      Neurologist Dr Andrew Blumenfeld explains in this 6-minute video >

      Find out how to administer BOTOX®

      Learn about the PREEMPT treatment paradigm: an evidence-based approach to help you achieve optimal clinical outcomes in patients with chronic migraine14 >

      CM: chronic migraine; CV: cardiovascular; ICHD: International Classification of Headache Disorders.

      TREATMENT OPTIONS FOR CHRONIC MIGRAINE

       

      References

      1. AbbVie Data on file. Approval Dates for BOTOX® in UK. UK-BTX-230044. April 2023
      2. Allergan. Data on file. INT/0423/2016
      3. Aurora S K, Winner P et al. Onabotulinum toxin A for treatment of chronic migraine: pooled analyses of the 56-week PREEMPT clinical program. Headache. 2011;51(9):1358-1373
      4. Blumenfeld A M, Stark R J et al. Long-term study of the efficacy and safety of Onabotulinum toxin A for the prevention of chronic migraine: COMPEL study. J Headache Pain. 2018;19(1):13
      5. BOTOX® Summary of Product Characteristics. Available from: https://www.medicines.org.uk/emc/product/859/smpc.
      6. Davies P T G, Lane R J M et al. The long and winding road: the journey taken by headache sufferers in search of help. Prim Health Care Res Dev. 2019;20:e4
      7. Natoli J L, Manack A et al. Global prevalence of chronic migraine: a systematic review. Cephalalgia. 2010;30(5):599-609
      8. National Institute for Health and Care Excellence (NICE). CG150: Headaches in over 12s: diagnosis and management. Available at: www.nice.org.uk. Accessed January 2025
      9. Schwedt T J. Chronic migraine. BMJ 2014;348:g1416
      10. National Institute of Health and Care Excellence (NICE) clinical knowledge summary (CKS). Migraine. Available at: https://cks.nice.org.uk. Accessed January 2025
      11. Buse D C, Manack A N et al. Chronic migraine prevalence, disability, and sociodemographic factors: results from the American Migraine Prevalence and Prevention Study. Headache. 2012;52(10):1456-1470
      12. Loder E, Rizzoli P. Pharmacologic prevention of migraine: a narrative review of the state of the art in 2018. Headache. 2018;58(Suppl 3):218-229
      13. Woolley J M, Bonafede M M et al. Migraine prophylaxis and acute treatment patterns among commercially insured patients in the United States. Headache. 2017;57(9):1399-1408
      14. Blumenfeld A M, Silberstein S D et al. Insights into the functional anatomy behind the PREEMPT injection paradigm: guidance on achieving optimal outcomes. Headache. 2017;57(5):766-777

       

      References

      1. AbbVie Data on file. Approval Dates for BOTOX® in UK. UK-BTX-230044. April 2023
      2. Allergan. Data on file. INT/0423/2016
      3. Aurora S K, Winner P et al. Onabotulinum toxin A for treatment of chronic migraine: pooled analyses of the 56-week PREEMPT clinical program. Headache. 2011;51(9):1358-1373
      4. Blumenfeld A M, Stark R J et al. Long-term study of the efficacy and safety of Onabotulinum toxin A for the prevention of chronic migraine: COMPEL study. J Headache Pain. 2018;19(1):13
      5. BOTOX® Summary of Product Characteristics. Available from: https://www.medicines.org.uk /emc/product/859/smpc.
      6. Davies P T G, Lane R J M et al. The long and winding road: the journey taken by headache sufferers in search of help. Prim Health Care Res Dev. 2019;20:e4
      7. Natoli J L, Manack A et al. Global prevalence of chronic migraine: a systematic review. Cephalalgia. 2010;30(5):599-609
      8. National Institute for Health and Care Excellence (NICE). CG150: Headaches in over 12s: diagnosis and management. Available at: www.nice.org.uk. Accessed January 2025
      9. Schwedt T J. Chronic migraine. BMJ 2014;348:g1416
      10. National Institute of Health and Care Excellence (NICE) clinical knowledge summary (CKS). Migraine. Available at: https://cks.nice.org.uk. Accessed January 2025
      11. Buse D C, Manack A N et al. Chronic migraine prevalence, disability, and sociodemographic factors: results from the American Migraine Prevalence and Prevention Study. Headache. 2012;52(10):1456-1470
      12. Loder E, Rizzoli P. Pharmacologic prevention of migraine: a narrative review of the state of the art in 2018. Headache. 2018;58(Suppl 3):218-229
      13. Woolley J M, Bonafede M M et al. Migraine prophylaxis and acute treatment patterns among commercially insured patients in the United States. Headache. 2017;57(9):1399-1408
      14. Blumenfeld A M, Silberstein S D et al. Insights into the functional anatomy behind the PREEMPT injection paradigm: guidance on achieving optimal outcomes. Headache. 2017;57(5):766-777

      Please refer to the BOTOX® Summary of Product Characteristics for further information on adverse events, contraindications and special warnings and precautions for use. The BOTOX® Summary of Product Characteristics can be found here

      BOTOX® PRESCRIBING INFORMATION

      By clicking the link above you will leave the AbbVie Pro website and be taken to the eMC PI portal website.

      Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk

      Adverse events should also be reported to AbbVie on GBPV@abbvie.com 

       

      Date of preparation: January 2025. UK-BCM-240124.

       

       

      Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk or via the MHRA Yellow Card app, available in the Google Play or Apple App Stores. Adverse events should also be reported to AbbVie on GBPV@abbvie.com

       

      This website is for UK Healthcare Professionals only

      UK-ABBV-230225. Date of preparation June 2023. This website has been developed and funded by AbbVie Ltd.

      © 2023 AbbVie Ltd. All rights reserved. Registered Number: 08004972 England.