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      • This website is for UK Healthcare Professionals only
      Prescribing Information
      BOTOX® SMPC
      RESOURCES

      +30 YEARS' GLOBAL EXPERIENCE
      ACROSS MULTIPLE INDICATIONS1-4

       

      FOCAL SPASTICITY

      BOTOX® is indicated for the symptomatic treatment of focal spasticity, including: upper limb spasticity in adults and ankle and foot disability due to lower limb spasticity in adults.5
      Prescribing Information
      BOTOX® SMPC
      RESOURCES

      +30 YEARS' GLOBAL EXPERIENCE ACROSS MULTIPLE INDICATIONS1-4

      FOCAL SPASTICITY

      BOTOX® is indicated for the symptomatic treatment of focal spasticity, including: upper limb spasticity in adults and ankle and foot disability due to lower limb spasticity in adults.5

      UK-BNO-240014. DOP: June 2024.

      Post-stroke spasticity (PSS) has a significant impact on daily life6,7

       

      PSS has a significant impact on a stroke survivor’s daily life, impeding basic tasks, such as eating and self-care6,8,9

      Intermittent or sustained involuntary activation of muscles6

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      Psychological consequences such as poor self-esteem and self image8

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      Interference with balance and movement, including decline in ability to walk6,9

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      Potential inability to perform activities of daily living and limit ability to engage in activities outside the home9

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      Increased rate of fractures as a consequence of increased risk of falls9

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      PSS: post-stroke spasticity.

      IDENTIFY AND MANAGE YOUR PSS PATIENTS

       

      References

      1. Allergan. Data on file. INT/0423/2016
      2. Aurora SK, et al. Onabotulinum toxin A for treatment of chronic migraine: pooled analyses of the 56-week PREEMPT clinical program. Headache 2011;51(9):1358–73
      3. Blumenfeld AM, et al. Long-term study of the efficacy and safety of Onabotulinum toxin A for the prevention of chronic migraine: COMPEL study. J Headache Pain 2018;19(1):13
      4. AbbVie Data on file. Approval Dates for BOTOX® in UK. UK-BTX-230044. April 2023
      5. BOTOX® Summary of Product Characteristics. Available from: https://www.medicines.org.uk/emc/product/859/smpc. Accessed June 2024
      6. Kheder A and Nair KP. Spasticity: pathophysiology, evaluation and management. Pract Neurol 2012;12(5):289–98
      7. Urban PP, et al. Occurrence and clinical predictors of spasticity after ischemic stroke. Stroke 2010;41(9):2016–20
      8. Royal College of Physicians. Spasticity in adults: management using botulinum toxin. National guidelines 2018. Available at: https://www.rcplondon.ac.uk/guidelines-policy-adulats-management-using-botulinum-toxin. Accessed June 2024
      9. Esquenazi A. The human and economic burden of post-stroke spasticity and muscle overactivity. JCOM 2011;18:607–14

       

      References

      1. Allergan. Data on file. INT/0423/2016
      2. Aurora SK, et al. Onabotulinum toxin A for treatment of chronic migraine: pooled analyses of the 56-week PREEMPT clinical program. Headache 2011;51(9):1358–73
      3. Blumenfeld AM, et al. Long-term study of the efficacy and safety of Onabotulinum toxin A for the prevention of chronic migraine: COMPEL study. J Headache Pain 2018;19(1):13
      4. AbbVie Data on file. Approval Dates for BOTOX® in UK. UK-BTX-230044. April 2023
      5. BOTOX® Summary of Product Characteristics. Available from: https://www.medicines.org.uk /emc/product/859/smpc. Accessed June 2024
      6. Kheder A and Nair KP. Spasticity: pathophysiology, evaluation and management. Pract Neurol 2012;12(5):289–98
      7. Urban PP, et al. Occurrence and clinical predictors of spasticity after ischemic stroke. Stroke 2010;41(9):2016–20
      8. Royal College of Physicians. Spasticity in adults: management using botulinum toxin. National guidelines 2018. Available at: https://www.rcplondon.ac.uk /guidelines-policy-adulats-management-using-botulinum-toxin. Accessed June 2024
      9. Esquenazi A. The human and economic burden of post-stroke spasticity and muscle overactivity. JCOM 2011;18:607–14

      Please refer to the BOTOX® Summary of Product Characteristics for further information on adverse events, contraindications and special warnings and precautions for use.

      BOTOX® PRESCRIBING INFORMATION

       

      Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/ or via the MHRA Yellow Card app, available in the Google Play or Apple App Stores.

      Adverse events should also be reported to AbbVie on GBPV@abbvie.com 

       

      Date of preparation: June 2024. UK-BTX-240032.

       

       

      Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk or via the MHRA Yellow Card app, available in the Google Play or Apple App Stores. Adverse events should also be reported to AbbVie on GBPV@abbvie.com

       

      This website is for UK Healthcare Professionals only

      UK-ABBV-230225. Date of preparation June 2023. This website has been developed and funded by AbbVie Ltd.

      © 2023 AbbVie Ltd. All rights reserved. Registered Number: 08004972 England.