VENCLYXTO® is a selective, oral, first-in-class BCL-2 inhibitor that targets BCL-2 overexpression, which helps to restore the process of apoptosis in CLL cells

VENCLYXTO® selectively binds to BCL-2, displacing pro-apoptotic proteins and triggering events that lead to apoptosis1

CLL=chronic lymphocytic leukaemia; 1L=first line; 2L+=second line + later lines of therapy; HR=hazard ratio; CI=confidence interval; PFS=progression-free survival; BR=bendamustine + rituximab; VEN+R=VENCLYXTO® + rituximab; BCL-2=B-cell lymphoma 2.


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Reference: 1. VENCLYXTO® Summary of Product Characteristics available at www.medicines.ie 

 IE-VNCCLL-230070  | Date of preparation: December 2023